Validation of treatment planning system using simulation PRIMO code.

Introduction: In radiation therapy, in order to double-check the dosimetric results of the main treatment planning system (TPS), a distinct TPS, with few capacitances in terms of contouring and a variety of dose calculation algorithms is used. This system has the capability to double check the planification and the accurate prediction of dose distribution in order to be ensured of the accuracy of the primary TPS results. The purpose of this study was to investigate the performance of Monte Carlo based algorithm, PRIMO, to double check the primary treatment planning software, and resolving the problem of limited budgets of radiotherapy centers in purchasing such systems. The present study evaluate the validation of the PRIMO code, in simulation of conformal treatments, which was performed with an Elekta Precise linear accelerator and an ISOgray treatment planning system.     Materials and Methods: In this study, the PRIMO code version 0.3.1.1626 was used. This code contains the geometry of Eleckta, Varian, Siemens linear accelerators and also CyberKnife system. The CT images of the Alderson Rando phantom, and the slab water phantom, contouring and treatment planning including photon energy, treatment fields and dose prescription point which was taken from ISOgray system in Dicom format were inputs of the PRIMO software. DICOM Editor Tools was used to solve the possible problems in reading these dicom files. To accelerate the simulation, the phase space files of a 6 MV photon beam derived from the International Atomic Energy Agency (IAEA) database.     Results: The gamma criteria of 3%/. 3 was used to compare the calculation results the simulation PRIMO code with ISOgray TPS system.   Conclusion: The results of this study indicate the potential of the PRIMO code for treatment planning in radiation therapy.